The SUSE Linux guys just launched a new service called SUSE Studio. With it, you can create an operating system running SUSE, and your own checklist of packages. If you watch the screencast, you see that he creates a Linux distribution that has PHP and MySQL running out of the box.
This seems like the perfect solution for creating a Drupal Operating System that's ready for both Drupal development and runtime right when you install it on your machine. All we'd have to do is have the Drupal packages ready!